Mar 18, 2026
Short answer: Tirzepatide most commonly causes nausea (~44%), diarrhea (~30%), vomiting (~25%), and constipation (~22%). These GI effects usually peak in weeks 2–4 and often improve by weeks 8–12 as the body adapts. Serious events such as pancreatitis and gallbladder disease are uncommon but require prompt medical attention. What is tirzepatide? Tirzepatide is a dual […]