Mar 30, 2026
Tirzepatide 2.5mg is the mandatory FDA-approved starting dose for all patients beginning Zepbound or Mounjaro, regardless of body weight or prior GLP-1 experience. It is a 4-week tolerability phase — not a therapeutic weight loss dose — designed to let the gastrointestinal system adapt before escalation to 5mg. Most patients experience mild to moderate nausea […]